师资力量

研究方向聚焦于免疫信息学、肿瘤信息学相关的算法研发及临床数据挖掘。发表学术论文40余篇，代表性工作发表于Signal Transaction and Targeted Therapy，Nature Communications，Cell Discovery，Nucleic Acids Research，Briefings in Bioinformatics等国际知名学术期间。主持国家自然科学基金面上/青年，上海市科委基金多项。

教育经历

2007-2011武汉理工大学，工学学士

2011-2016同济大学，理学博士

工作经历

2016-2018复旦大学，博士后

2018-2022复旦大学附属公共卫生临床中心， 助理研究员/超算中心负责人

2022-至今 复旦大学附属中山医院， 青年研究员

2024-至今 复旦大学智能医学研究院， 青年研究员

主持科研项目

国家自然科学基金面上项目

国家自然科学基金青年项目

上海市科委青年英才扬帆计划

人社部/博士后科学基金会博新计划

博士后科学基金

上海市地高建人才引进项目

复旦大学AI for Science专项

复旦大学临床专职科研团队项目

国家重点研发计划（项目骨干）

代表性论文

第一作者（含共一）论文：

1. Yiwen Wei^#, Tianyi Qiu^#, et al. Advances of computational methods enhance the development of multi-epitope vaccines. Briefings in Bioinformatics (2025). 26(1). bbaf055.

2. Xiaoyu Zhao^#, Tianyi Qiu^#, et al. Potent and broadly neutralizing antibodies against sarbecoviruses induced by sequential COVID-19 vaccination. Cell Discovery (2024). 10:14.

3. Ping Zhou^#, Tianyi Qiu^#, et al. One HA stalk topping multiple heads as a novel influenza vaccine. Emerging Microbes & Infections (2024). VOL.13, 2290838.

4. Wanchun Nie^#, Tianyi Qiu^#, et al. Advances in phage–host interaction prediction: in silico method enhances the development of phage therapies. Briefings in Bioinformatics (2024), 25(3), bbae117.

5. Tianyi Qiu^#, Jingxuan Qiu^#, et al. A benchmark dataset of protein antigens for antigenicity measurement. Scientific Data (2020),7:212.

6. Tianyi Qiu^#, Mao Tian Tian^#, et al. Identification of potential cross-protective epitope between a new type of coronavirus (2019-nCoV) and severe acute respiratory syndrome virus. Journal of Genetics and Genomics. (2020). DOI: https://doi.org/10.1016/j.jgg.2020.01.003.

7. Jingxuan Qiu^#, Tianyi Qiu^#, et al. Predicting the antigenic relationship of foot-and-mouth disease virus for vaccine selection through a computational model. IEEE/ACM transactions on computational biology and bioinformatics. (2019). DOI: 10.1109/TCBB.2019.2923396.

8. Tianyi Qiu^#, Yiyan Yang^#, Jingxuan Qiu^# et al. CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens. Nature Communications. (2018) 9:1772.

9. Tianyi Qiu^#, Dingfeng Wu^# et al. Finding the molecular scaffold of nuclear receptor inhibitors through high-throughput screening based on Proteochemometric modelling. Journal of cheminformatics. (2018) 10:21.

10. Tianyi Qiu, Jingxuan Qiu et al. The recent progress in proteochemometric modelling: focusing on target descriptors, cross-term descriptors and application scope. Briefings in Bioinformatics. 2017 Jan; 18(1): 125-136.

11. Dingfeng Wu^#, Tianyi Qiu^# et al. Systematic toxicity mechanism analysis of proton pump inhibitors: an in silico study. Chemical Research in Toxicology. 2015 Mar 16;28(3):419-30.

12. Tao Qi^#, Tianyi Qiu^# et al. SEPPA 2.0--more refined server to predict spatial epitope considering species of immune host and subcellular localization of protein antigen. Nucleic Acids Research. 2014 Jul;42(Web Server issue): W59-63.

通讯作者论文：

1. Jingxuan Qiu, et al. Tianyi Qiu*. NRIP: A model for NNRTI-RT interaction prediction and enabling virtual screening of anti-HIV natural compounds. Journal of Chemical Information and Modeling. (2025). Doi: 10.1021/acs.jcim.5c01588.

2. Zikun Chen, et al. Tianyi Qiu*. ONMR: an orthopedic and nutritional Mendelian randomization database. npj Science of Food. (2025) 9:190.

3. Yewei Cun, et al. Tianyi Qiu*. SITA: Predicting site-specific immunogenicity for therapeutic antibodies. Journal of Pharmaceutical Analysis. (2025) 15: 101316.

4. Jingxuan Qiu, et al. Tianyi Qiu*. Integrated in-silico design and in vivo validation of multi-epitope vaccines for norovirus. Virology Journal. (2025) 22:166.

5. Genhui Zheng, et al. Tianyi Qiu*. PbsNRs: predict the potential binders and scaffolds for nucleic receptors. Briefings in Bioinformatics. (2025). 26(1), bbae710.

6. Wanchun Nie, et al. Tianyi Qiu*. PB-LKS: a Python package for predicting Phage-Bacteria interaction through Local K-mer Strategy. Briefings in Bioinformatics. (2024). Doi: 10.1093/bib/bbae010.

7. Zuojing Yin, et al. Tianyi Qiu*. Dynamically adjustable SVEIR(MH) model of multiwave epidemics: Estimating the effects of public health measures against COVID-19. Journal of Medical Virology. (2023) DOI: 10.1002/jmv.29301.

8. Bingyu Li, et al. Tianyi Qiu*, Jianmin Fang*. Neo-intline: integrated pipeline enables neoantigen design through the in-silico presentation of T-cell epitope. Signal Transduction and Targeted Therapy. (2023) 8:397.

9. Tianyi Qiu*, et al. Zhiwei Cao*. SEPPA-mAb: spatial epitope prediction of protein antigens for mAbs. Nucleic Acids Research. (2023) W1-W7.

10. Li-na Chen, et al. Tianyi Qiu*, Xuanyi Wang*. Molecular epidemiology analysis of symptomatic and asymptomatic norovirus infections in Chinese infants. Virology Journal. (2023) 20:60.

11. Zhi-lu Chen, et al. Tianyi Qiu*, Xiaoyan Zhang*, Jianqing Xu*. Revealing the characteristics of ZIKV infection through tissue-specific transcriptome sequencing analysis. BMC Genomics. (2022) 23:697.

12. Sijie Wang, et al. Tianyi Qiu*, Shengli Chen*, Xuanyi Wang*. Genetic characterization of two G8P[8] rotavirus strains isolated in Guangzhou, China, in 2020/21: evidence of genome reassortment. BMC Infectious Diseases. (2022) 22:579.

13. Jingxuan Qiu, et al. Tianyi Qiu*. Univ-flu: A structure-based model of influenza A virus hemagglutinin for universal antigenic prediction. Computational and Structural Biotechnology Journal 20 (2022) 4656-4666.

14. Chen Zhou, et al. Tianyi Qiu*, Zhiwei Cao*. SEPPA 3.0-enhanced spatial epitope prediction enabling glycoprotein antigens. Nucleic Acids Research. 2019 Jul;47(Web Server issue): W388-W394.