师资力量

复旦大学智能医学研究院，青年研究员

周欣专注于代谢组、免疫组和微生物组等多组学数据的整合研究。

在人类微生物组计划的框架下，周欣系统地解析了肠道微生物组与宿主免疫系统、代谢系统之间的相互作用，并结合其对心血管系统、淋巴系统、糖尿病等疾病的机制研究，深入探讨了个体微生物组对宿主免疫调控机制的潜在影响，揭示了微生物组与临床表型之间的复杂关联，为理解疾病的发生发展机制提供了重要视角。

主要经历

2024-05 至 2025-04,美国斯坦福大学医学院，Basic Life Research Scientist

2019-06 至 2024-04, 美国斯坦福大学医学院，博士后

2013-09 至 2019-05, 美国康涅狄格大学, 博士

2011-12 至 2013-06，美国凯斯西储大学，科研助理

2007-09 至 2011-07, 复旦大学, 学士

主持项目：

National Institute on Aging, Resource Centers for Minority Aging Research Fellowship, P30-AG059307, Relating gastrointestinal dysbiosis in pulmonary arterial hypertension to rapid vascular aging., 2021-06 至 2022-06, 结题, 主持

代表性论著

(1) Xin Zhou; Ariel B Ganz; Andre Rayner; Tess Yan Cheng; Haley Oba; Benjamin Rolnik; Samuel Lancaster; Xinrui Lu; Yizhou Li; Jethro S Johnson; Rebecca Hoyd; Daniel J Spakowicz; George MSlavich; Michael P Snyder ; Dynamic human gut microbiome and immune shifts during an immersive psychosocial intervention program, Brain, Behavior, and Immunity, 2024, 125(1): 428-443 (共同第一作者 )

(2) Xin Zhou; Xiaotao Shen; Jethro S. Johnson; Daniel J. Spakowicz; Melissa Agnello; Wenyu Zhou; Monica Avina; Alexander Honkala; Faye Chleilat; Shirley Jingyi Chen; Kexin Cha; Shana Leopold; Chenchen Zhu; Lei Chen; Lin Lyu; Daniel Hornburg; Si Wu; Xinyue Zhang; Chao Jiang; Liuyiqi Jiang; Lihua Jiang; Ruiqi Jian; Andrew W. Brooks; Meng Wang; Kevin Contrepois; Peng Gao; Sophia Miryam Schussler-Fiorenza Rose; Thi Dong Binh Tran; Hoan Nguyen; Alessandra Celli; Bo-Young Hong; Eddy J. Bautista; Yair Dorsett; Paula B. Kavathas; Yanjiao Zhou; Erica Sodergren; George M. Weinstock; Michael P. Snyder ; Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease, Cell Host Microbe, 2024 (共同第一作者 )

(3) Zhiyun Yu; Xin Zhou; Ziyi Liu; Victor Pastrana-Gomez; Yu Liu; Minzhe Guo; Lei Tian; Timothy J Nelson; Nian Wang; Seema Mital; David Chitayat; Joseph C. Wu; Marlene Rabinovitch; Joseph C. Wu; Xin Li; Yifei Miao; Mingxia Gu ; KMT2D-NOTCH Mediates Coronary Abnormalities in Hypoplastic Left Heart Syndrome, Circulation Research, 2022, 131(3): 280-282 (共同第一作者 )

(4) Stanley G. Rockson; Xin Zhou; Lan Zhao; Davood K. Hosseini; Xinguo Jiang; Andrew J.Sweatt; Dongeon Kim; Wen Tian; Michael P. Snyder; Mark R. Nicolls ; Exploring disease interrelationships in patients with lymphatic disorders: A single center retrospective experience, Clinical and Translational Medicine, 2022, 12(4): e760 (共同第一作者 )

(5) Xin Zhou; Jethro S. Johnson; Daniel Spakowicz; Wenyu Zhou; Yanjiao Zhou; Erica Sodergren; Michael Snyder; George M. Weinstock ; Longitudinal Analysis of Serum Cytokine Levels and Gut Microbial Abundance Links IL-17/IL-22 With Clostridia and Insulin Sensitivity in Humans, Diabetes, 2020, 69(8): 1833-1842 (共同第一作者 )

(6) Xin Zhou; Xin Chen; Mark M. Davis; Michael P. Snyder ; Embracing Interpersonal Variability of Microbiome in Precision Medicine, Phenomics, 2025(共同第一作者 )

(7) Xin Zhou; Wen Tian; Shenbiao Gu; Marlene Rabinovitch; Mark R. Nicolls; Michael P. Snyder; Microbiome–Immune Interaction in Pulmonary Arterial Hypertension: What Have We Missed?, Research, 2025, 8: 1-4 (唯一第一作者 )

(8) Shuting Xia; Diya Jiang; Qianyi Zhou; Hairong Lyu; Anita Y. Voigt; Xin Zhou; Zhemin Zhou; Yuan Huang ; Unlocking the healthy human microbiome: Redefining core microbial signatures, Acta Pharmaceutica Sinica B, 2025, 15(2): 1189-1192(共同通讯作者 )

(9) Xiaotao Shen; Chuchu Wang; Xin Zhou; Wenyu Zhou; Daniel Hornburg; Si Wu; Michael P.Snyder ; Nonlinear dynamics of multi-omics profiles during human aging, Nature Aging, 2024,4:1619-1634

(10) Yiwen Cheng; Xia Liu; Feng Chen; Benjamin M. Rolnik; Faye Chleilat; Zongxin Ling; Michael P. Snyder; Xin Zhou ; The Roles and Mechanisms of Gut Microbiota in Food Allergy, Advanced Gut &Microbiome Research, 2023, 2023: 1-16(共同通讯作者)

(11) Lin Lyu; Xue Li; Ru Feng; Xin Zhou; Tuhin K. Guha; Xiaofei Yu; Guo Qiang Chen; Yufeng Yao; Bing Su; Duowu Zou; Michael P. Snyder; Lei Chen ; Simultaneous profiling of host expression and microbial abundance by spatial metatranscriptome sequencing, Genome Research, 2023, 33(3):401-411 (共同第一作者 )

(12) Daniel Hornburg; Si Wu; Mahdi Moqri; Xin Zhou; Kevin Contrepois; Nasim Bararpour; Gavin M. Traber; Baolong Su; Ahmed A. Metwally; Monica Avina; Wenyu Zhou; Jessalyn M. Ubellacker; Tejaswini Mishra; Sophia Miryam Schüssler-Fiorenza Rose; Paula B. Kavathas; Kevin J. Williams; Michael P. Snyder ; Dynamic lipidome alterations associated with human health, disease and ageing, Nature Metabolism, 2023, 5(9): 1578-1594

(13) Xin Zhou; Baohong Wang; Patrick C. Demkowicz; Jethro S. Johnson; Yanfei Chen; Daniel J.Spakowicz; Yanjiao Zhou; Yair Dorsett; Lei Chen; Erica Sodergren; George A. Kuchel; George M.Weinstock ; Exploratory studies of oral and fecal microbiome in healthy human aging, Frontiers in Aging, 2022, 3(1002405) (共同第一作者, 共同通讯作者 )

(14) Wenyu Zhou; M.Reza Sailani; Kévin Contrepois; Yanjiao Zhou; Sara Ahadi; Shana R.Leopold; Martin J.Zhang; Varsha Rao; Monika Avina; Tejaswini Mishra; Jethro Johnson; Brittany Lee-McMullen; Songjie Chen; Ahmed A.Metwally; Thi Dong Binh Tran; Hoan Nguyen; Xin Zhou; Brandon Albright; Bo-Young Hong; Lauren Petersen; Eddy Bautista; Blake Hanson; Lei Chen; Daniel Spakowicz; Amir Bahmani; Denis Salins; Benjamin Leopold; Melanie Ashland; Orit Dagan-Rosenfeld; Shannon Rego; Patricia Limcaoco; Elizabeth Colbert; Candice Allister; Dalia Perelman; Colleen Craig; Eric Wei; Hassan Chaib; Daniel Hornburg; Jessilyn Dunn; Liang Liang; Sophia Miryam Schüssler-Fiorenza Rose; Kim Kukurba; Brian Piening; Hannes Rost; David Tse; Tracey McLaughlin; Erica Sodergren; George M.Weinstock; Michael Snyder ; Longitudinal multi-omics of host–microbe dynamics in prediabetes, Nature, 2019, 569(7758): 663-671

(15) Jenna M.Bartley; Xin Zhou; George A.Kuchel; George M.Weinstock; Laura Haynes ; Impact of Age, Caloric Restriction, and Influenza Infection on Mouse Gut Microbiome: An Exploratory Studyof the Role of Age-Related Microbiome Changes on Influenza Responses, Frontiers in Immunology, 2017, 8: 1164 (共同第一作者 )