Postdoctoral Position Available in Microbiome and MicrobiologyResearch

The Mani Laboratory (https://www.einsteinmed.edu/faculty/5615/sridhar-mani/),housed in the Chanin Building, at the Departments of Medicine, Genetics and Pharmacology and The Cancer Institute and Einstein-Mount Sinai Diabetes Research Center of The Albert Einstein College of Medicine, INC(www.einsteinmed.edu) has an open position for a highly motivated postdoctoral fellow to be part of an expanding research program on novel aspects of the mammalian microbiome.Relevant Laboratory Research Focus: We have discovered a new phenomenon related to how gut bacteria influence intestinal inflammation (DOI: 10.1053/j.gastro.2021.03.017). We have isolated a super-swarming strain from mice with colitis (and a near identical poor swarmer from control mice). These strains affect the inflammatory phenotype in mice. We are interested in developing a high throughput genetic mutant library of both strains where the strains are screened for the swarmer/swim/growth phenotype. We want to create genetically or chemically marked fluorescent strains in vitro and in vivo (mice). We are also interested in developing modified transcriptional recording systems (such as doi: 10.1038/s41596-023-00819-6) that would record how swarm/swim/growth is affected when our bacteria are plated and in mice. Finally, we are interested in the secretomes of our isolates as they mechanistically relate to abrogating intestinal inflammation. Each point is a project, and successful candidates can choose one or more to focus on or develop new ideas as projects evolve to focus on.

Scientific Environment within and outside the Laboratory (collaborations): A longstanding tradition of the laboratory is cooperative and collaborative exchange with knowledgeable labs that use complementary expertise or bioinformatics. In all these associations, our laboratory is an active participant, wherein the student or fellow is encouraged to learn further by visiting and partaking in cross-collaborative experiments.

Financial Support: The new Einstein base salary (no prior postdoctoral experience) is $ 58,179 (effective 3/1/2023). For full details, please visit https://www.einsteinmed.edu/research/belfer- institute/postdoctoral-policies/ . Successful applicants will receive a generous salary based on NIH and Institutional guidelines and benefits, including College-owned postdoctoral housing.

Candidate Profile:

1. Demonstrated academic and research accomplishments.

2. Prior experience in bacterial genetics, specifically genome-wide mutagenesis techniques in bacteria, bioinformatics, and protein biochemistry

Opening: March 1, 2024.

Application Process:

Please e-mail your CV and cover letter focusing on your interests and goals, along with names and contact details of three referees to: smani855@gmail.com OR sridhar.mani@einsteinmed.edu

The Albert Einstein College of Medicine is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Einstein seeks candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence, and the communities we serve.